Article

Remodeling and activation mechanisms of outer arm dyneins revealed by cryo-EM

2020-11-30

Abstract excerpt

Cilia are thin microtubule-based protrusions of eukaryotic cells. The swimming of ciliated protists and sperm cells is propelled by the beating of cilia. Cilia propagate the flow of mucus in the trachea and protect the human body from viral infections. The main force generators of ciliary beating are the outer dynein arms (ODAs) which attach to the doublet microtubules. The bending of cilia is driven by the ODAs’...

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Literature Corpus work: 4f4c700e-d595-5229-8c24-cdb593346c1b
DOI: 10.1101/2020.11.30.404319

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