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Article

Cryoelectron tomography reveals doublet-specific structures and unique interactions in the I1 dynein.

Proceedings of the National Academy of Sciences of the United States of America - 24 Jul 2012

Heuser Thomas, Barber Cynthia F, Lin Jianfeng, Krell Jeremy, Rebesco Matthew, Porter Mary E, Nicastro Daniela

Abstract excerpt

Cilia and flagella are highly conserved motile and sensory organelles in eukaryotes, and defects in ciliary assembly and motility cause many ciliopathies. The two-headed I1 inner arm dynein is a critical regulator of ciliary and flagellar beating. To understand I1 architecture and function better, we analyzed the 3D structure and composition of the I1 dynein in Chlamydomonas axonemes by cryoelectron tomography...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 22733763
DOI: 10.1073/pnas.1120690109
PMCID: PMC3409752

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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