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Article

The dynein regulatory complex is the nexin link and a major regulatory node in cilia and flagella.

The Journal of cell biology - 14 Dec 2009

Heuser Thomas, Raytchev Milen, Krell Jeremy, Porter Mary E, Nicastro Daniela

Abstract excerpt

Cilia and flagella are highly conserved microtubule (MT)-based organelles with motile and sensory functions, and ciliary defects have been linked to several human diseases. The 9 + 2 structure of motile axonemes contains nine MT doublets interconnected by nexin links, which surround a central pair of singlet MTs. Motility is generated by the orchestrated activity of thousands of dynein motors, which drive...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 20008568
DOI: 10.1083/jcb.200908067
PMCID: PMC2806320

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The dynein regulatory complex is the nexin link and a major regulatory node in cilia and flagella.PMID 20008568Read ↗

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