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Article

Detailed structural and biochemical characterization of the nexin-dynein regulatory complex.

Molecular biology of the cell - 15 Jan 2015

Oda Toshiyuki, Yanagisawa Haruaki, Kikkawa Masahide

Abstract excerpt

The nexin-dynein regulatory complex (N-DRC) forms a cross-bridge between the outer doublet microtubules of the axoneme and regulates dynein motor activity in cilia/flagella. Although the molecular composition and the three-dimensional structure of N-DRC have been studied using mutant strains lacking N-DRC subunits, more accurate approaches are necessary to characterize the structure and function of N-DRC. In this...

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Identifiers

PMID: 25411337
DOI: 10.1091/mbc.E14-09-1367
PMCID: PMC4294676

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Source receipt: pubmed, retrieved 7 Sept 2026.

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