Article
Molecular architecture of inner dynein arms in situ in Chlamydomonas reinhardtii flagella.
The Journal of cell biology - 1 Dec 2008
Bui Khanh Huy, Sakakibara Hitoshi, Movassagh Tandis, Oiwa Kazuhiro, Ishikawa Takashi
Abstract excerpt
The inner dynein arm regulates axonemal bending motion in eukaryotes. We used cryo-electron tomography to reconstruct the three-dimensional structure of inner dynein arms from Chlamydomonas reinhardtii. All the eight different heavy chains were identified in one 96-nm periodic repeat, as expected from previous biochemical studies. Based on mutants, we identified the positions of the AAA rings and the N-terminal...
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