Article

Targeted dynein inhibition generates flagellar beating

2017-06-21

Abstract excerpt

<h4>SUMMARY</h4> Motile cilia and flagella are highly conserved organelles that are essential for the normal development and health of many eukaryotes including humans. To reveal the molecular mechanism of motility, we used cryo-electron tomography of active sea urchin sperm flagella to directly visualize the macromolecular complexes and their structural changes during flagellar beating. We resolved distinct conf...

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Literature Corpus work: dcc75a12-2b80-5ec8-8848-b19c153f8e46
DOI: 10.1101/153254

Open publication

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