Article

Circulating Clonally Expanded T Cells Reflect Functions of Tumor Infiltrating T Cells

2020-10-02

Abstract excerpt

Understanding the relationship between tumor and peripheral immune environments could allow longitudinal immune monitoring in cancer. Here, we examined whether T cells that share the same TCRαβ and are found in both tumor and blood can be interrogated to gain insight into the ongoing tumor T cell response. Paired transcriptome and TCRαβ repertoire of circulating and tumor-infiltrating T cells were analyzed from ma...

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Literature Corpus work: 4ed29750-943f-56d4-9e1c-3eddc4988551
DOI: 10.1101/2020.09.30.321240

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