Article

Regional and clonal T cell dynamics at single cell resolution in immune checkpoint blockade

2021-09-27

Abstract excerpt

<h4>ABSTRACT</h4> Paired T cell receptor and RNA single cell sequencing (scTCR/RNA-seq) has allowed for enhanced resolution of clonal T cell dynamics in cancer. Here, we report a scTCR/RNA-seq dataset of 162,062 single T cells from 31 tissue regions, including tumor, adjacent normal tissues, and lymph nodes (LN), from three patients who underwent resections for progressing lung cancers after immune checkpoint blo...

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Literature Corpus work: 991a9e17-5ba9-5931-b10d-9b3ad05f1b21
DOI: 10.1101/2021.09.27.461389

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