Article

Rare Subset of T Cells Form Heterotypic Clusters with Circulating Tumor Cells to Foster Cancer Metastasis

2025-04-03

Abstract excerpt

The immune ecosystem is central to maintaining effective defensive responses. However, how immune cells in the periphery blood interact with circulating tumor cells (CTCs) – seeds of metastasis - remains largely understudied. Here, our analysis of the blood specimens (N=1,529) from patients with advanced breast cancer revealed that over 75% of the CTC-positive blood specimens contained heterotypic CTC clusters wit...

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Literature Corpus work: 69514f1f-8a1a-5a8c-b4ee-0d5973e825f5
DOI: 10.1101/2025.04.01.646421

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