Article

A Conserved Switch Controls Virulence, Sporulation, and Motility in <i>C. difficile</i>

2023-03-28

Abstract excerpt

<h4>SUMMARY</h4> Spore formation is required for environmental survival and transmission of the human enteropathogenic Clostridioides difficile . In all bacterial spore formers, sporulation is regulated through activation of the master response regulator, Spo0A. However, the factors and mechanisms that directly regulate C. difficile Spo0A activity are not defined. In the well-studied Bacillus species, Spo0A is...

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Literature Corpus work: 4e7d77ad-a4bc-5a00-8f5e-e0d1546dcdff
DOI: 10.1101/2023.03.28.534590

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