Article

Spo0A suppresses <i>sin</i> locus expression in <i>Clostridioides difficile</i>

2020-02-28

Abstract excerpt

Clostridioides difficile is the leading cause of nosocomial infection and is the causative agent of antibiotic-associated diarrhea. The severity of the disease is directly associated with the production of toxins, and spores are responsible for the transmission and persistence of the organism. Previously we characterized sin locus regulators SinR and SinR’, where SinR is the regulator of toxin production and spor...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: c96eca9a-c89e-5786-aa0e-2893ad2e01eb
DOI: 10.1101/2020.02.28.968834

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Spo0A suppresses <i>sin</i> locus expression in <i>Clostridioides difficile</i>DOI 10.1101/2020.02.28.968834Read

Spo0A Suppresses sin Locus Expression in Clostridioides difficile.Semantic proximity Read

Pleiotropic roles of Clostridium difficile sin locusSemantic proximity Read

A Conserved Switch Controls Virulence, Sporulation, and Motility in <i>C. difficile</i>Semantic proximity Read

A regulatory protein that represses sporulation in <i>Clostridioides difficile</i>Semantic proximity Read

A conserved switch controls virulence, sporulation, and motility in C. difficileSemantic proximity Read

The regulatory role of anti-sigma factor, RsbW, in <i>Clostridioides difficile</i> stress response, persistence and infectionSemantic proximity Read

Functional genomics reveals that Clostridium difficile Spo0A coordinates sporulation, virulence and metabolism.Semantic proximity Read

Global analysis of the sporulation pathway of Clostridium difficile.Semantic proximity Read

SpoIIID ‐mediated regulation of σ K function during C lostridium difficile sporulationSemantic proximity Read

RstA is a Major Regulator of <i>Clostridioides difficile</i> Toxin Production and MotilitySemantic proximity Read

RstA Regulation of <i>Clostridioides difficile</i> Toxin Production and Sporulation in Phenotypically Diverse StrainsSemantic proximity Read

A network of small RNAs regulates sporulation initiation in <i>C. difficile</i>Semantic proximity Read