Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Spo0A Suppresses sin Locus Expression in Clostridioides difficile.

mSphere - 4 Nov 2020

Dhungel Babita Adhikari, Govind Revathi

Abstract excerpt

Clostridioides difficile is the leading cause of nosocomial infection and is the causative agent of antibiotic-associated diarrhea. The severity of the disease is directly associated with toxin production, and spores are responsible for the transmission and persistence of the organism. Previously, we characterized sin locus regulators SinR and SinR' (we renamed it SinI), where SinR is the regulator of toxin...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Proteins
Share to Clostridioides difficile
Share to Gene Expression Regulation, Bacterial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Loci

Share to Promoter Regions, Genetic

Share to Protein Binding

Share to Spores, Bacterial

Share to Suppression, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 33148827
DOI: 10.1128/mSphere.00963-20
PMCID: PMC7643835

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Spo0A Suppresses sin Locus Expression in Clostridioides difficile.PMID 33148827Read ↗

Spo0A suppresses <i>sin</i> locus expression in <i>Clostridioides difficile</i>Semantic proximity Read ↗

Pleiotropic roles of Clostridium difficile sin locusSemantic proximity Read ↗

A conserved switch controls virulence, sporulation, and motility in C. difficileSemantic proximity Read ↗

Functional genomics reveals that Clostridium difficile Spo0A coordinates sporulation, virulence and metabolism.Semantic proximity Read ↗

A Conserved Switch Controls Virulence, Sporulation, and Motility in <i>C. difficile</i>Semantic proximity Read ↗

Global analysis of the sporulation pathway of Clostridium difficile.Semantic proximity Read ↗

A regulatory protein that represses sporulation in <i>Clostridioides difficile</i>Semantic proximity Read ↗

SpoIIID ‐mediated regulation of σ K function during C lostridium difficile sporulationSemantic proximity Read ↗

A network of small RNAs regulates sporulation initiation in Clostridioides difficileSemantic proximity Read ↗

RstA Regulation of <i>Clostridioides difficile</i> Toxin Production and Sporulation in Phenotypically Diverse StrainsSemantic proximity Read ↗

Spo0A differentially regulates toxin production in evolutionarily diverse strains of Clostridium difficile.Semantic proximity Read ↗

The Clostridium difficile spo0A gene is a persistence and transmission factor.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.