Article
The Phosphotransfer Protein CD1492 Represses Sporulation Initiation in Clostridium difficile.
Infection and immunity - 1 Dec 2016
Childress Kevin O, Edwards Adrianne N, Nawrocki Kathryn L, Anderson Sarah E, Woods Emily C, McBride Shonna M
Abstract excerpt
The formation of spores is critical for the survival of Clostridium difficile outside the host gastrointestinal tract. Persistence of C. difficile spores greatly contributes to the spread of C. difficile infection (CDI), and the resistance of spores to antimicrobials facilitates the relapse of infection. Despite the importance of sporulation to C. difficile pathogenesis, the molecular mechanisms controlling spore...
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