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Article

Global analysis of the sporulation pathway of Clostridium difficile.

PLoS genetics - 1 Jan 2013

Fimlaid Kelly A, Bond Jeffrey P, Schutz Kristin C, Putnam Emily E, Leung Jacqueline M, Lawley Trevor D, Shen Aimee

Abstract excerpt

The Gram-positive, spore-forming pathogen Clostridium difficile is the leading definable cause of healthcare-associated diarrhea worldwide. C. difficile infections are difficult to treat because of their frequent recurrence, which can cause life-threatening complications such as pseudomembranous colitis. The spores of C. difficile are responsible for these high rates of recurrence, since they are the major...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23950727
DOI: 10.1371/journal.pgen.1003660
PMCID: PMC3738446

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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