Article

Nomograms of Human Hippocampal Volume Shifted by Polygenic Scores

2022-02-19

Abstract excerpt

Nomograms are important clinical tools applied widely in both developing and aging populations. They are generally constructed as normative models identifying cases as outliers to a distribution of healthy controls. Currently used normative models do not account for genetic heterogeneity. Hippocampal Volume (HV) is a key endophenotype for many brain disorders. Here, we examine the impact of genetic adjustment on H...

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Literature Corpus work: 4e6b4ddf-3856-531f-af3a-eaef0c2eac28
DOI: 10.1101/2022.02.17.480931

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