Article

Integrative cross-omics and cross-context analysis elucidates molecular links underlying genetic effects on complex traits

2022-10-18

Abstract excerpt

<title>Abstract</title> <p>The proliferation of association results from large-scale genetic and genomic studies provides opportunities and challenges to elucidate the disease/trait mechanisms and their operating cellular contexts. Motivated by a multi-tissue multi-omics analysis using genetics, methylome and transcriptome data from the Genotype-Tissue Expression (GTEx) project, we propose a method, X-ING (Cross-...

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Literature Corpus work: 4e1be5bc-2bd5-5756-90ac-710ec4aa19e4
DOI: 10.21203/rs.3.rs-2137179/v1

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