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Article

Characterization of cross-tissue genetic-epigenetic effects and their patterns in schizophrenia

26 Feb 2018

Abstract excerpt

One of the major challenges in current psychiatric epigenetic studies is the tissue specificity of epigenetic changes since access to brain samples is limited. Peripheral tissues have been studied as surrogates but the knowledge of cross-tissue genetic-epigenetic characteristics remains largely unknown. In this work, we conducted a comprehensive investigation of genetic influence on DNA methylation across brain...

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PMID: 29482655
DOI: 10.1186/s13073-018-0519-4

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