Article
Methods of integrating data to uncover genotype-phenotype interactions.
Nature reviews. Genetics - 1 Feb 2015
Ritchie Marylyn D, Holzinger Emily R, Li Ruowang, Pendergrass Sarah A, Kim Dokyoon
Abstract excerpt
Recent technological advances have expanded the breadth of available omic data, from whole-genome sequencing data, to extensive transcriptomic, methylomic and metabolomic data. A key goal of analyses of these data is the identification of effective models that predict phenotypic traits and outcomes, elucidating important biomarkers and generating important insights into the genetic underpinnings of the...
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