Article

Recall by polygenic risk score in two biobanks supports a genomic approach for glaucoma detection

2025-08-05

Abstract excerpt

<title>Abstract</title> <p> Glaucoma is a highly heritable optic neuropathy and a leading cause of blindness; yet, glaucoma screening is challenging due to the time-consuming clinical methods required for disease identification and the imperfect accuracy of screening tests. We used genome-wide association study results to calculate a primary open angle glaucoma (POAG) polygenic risk score (PRS) for Mount Sinai B...

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Literature Corpus work: 4e1750df-5518-5324-b4e7-da8a92a25096
DOI: 10.21203/rs.3.rs-7159368/v1

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