Article

A sporadic Alzheimer’s blood-brain barrier model for developing ultrasound-mediated delivery of Aducanumab and anti-Tau antibodies

2022-03-07

Abstract excerpt

<h4>Rationale</h4> The blood-brain barrier (BBB) is a major impediment to therapeutic intracranial drug delivery for the treatment of neurodegenerative diseases, including Alzheimer’s disease (AD). Focused ultrasound applied together with microbubbles (FUS +MB ) is a novel technique to transiently open the BBB and increase drug delivery. Evidence suggests that FUS +MB is safe, however the effects of FUS +MB on...

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Literature Corpus work: 4d4ba003-e1bb-53a5-a2b4-fec2f0447301
DOI: 10.1101/2022.03.06.483200

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