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Alzheimer’s disease brain endothelial-like cells reveal differential drug transporter expression and modulation by potentially therapeutic focused ultrasound

2023-03-01

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold> The blood-brain barrier (BBB) has a major role in maintaining homeostasis of the brain. The primary function of the BBB is regulating the entry of molecules from the blood to the brain while protecting the brain from potentially harmful endogenous and exogenous substances. Transporters expressed in brain endothelial cells (BECs) mediate the uptake or efflux of co...

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Literature Corpus work
0fb45ac7-9157-5fcf-9075-ff41c4668c68
DOI
10.21203/rs.3.rs-2605800/v1
Open publication

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