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Article

Super-enhancer driven expression of BAHCC1 promotes melanoma cell proliferation and genome stability

2023-01-20

Abstract excerpt

Super enhancers (SE) are stretches of active enhancers ensuring high expression levels of key genes associated with cell function and survival. The identification of cancer-specific SE-driven genes and their functional characterization may prove to be a powerful means for the development of innovative therapeutic strategies. By performing epigenomic profiling in patient-derived short-term melanoma cultures, we ide...

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Identifiers and source

Literature Corpus work
4c0d87c4-7963-5aae-b0ef-617054482063
DOI
10.1101/2023.01.18.524519
Open publication

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Super-enhancer driven expression of BAHCC1 promotes melanoma cell proliferation and genome stabilityDOI 10.1101/2023.01.18.524519
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