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Bridging Genomic Research Disparities in Osteoporosis GWAS: Insights for Diverse Populations

24 May 2025

Abstract excerpt

PURPOSE OF REVIEW: Genome-wide association studies (GWAS) have significantly advanced osteoporosis research by identifying genetic loci associated with bone mineral density (BMD) and fracture risk. However, disparities persist due to the underrepresentation of non-European populations, limiting the applicability of polygenic risk scores (PRS). This review examines recent advancements in osteoporosis genetics,...

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PMID: 40411668
DOI: 10.1007/s11914-025-00917-2

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