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Article

Computational Characterization of Osteoporosis Associated SNPs and Genes Identified by Genome-Wide Association Studies.

PloS one - 1 Jan 2016

Qin Longjuan, Liu Yuyong, Wang Ya, Wu Guiju, Chen Jie, Ye Weiyuan, Yang Jiancai, Huang Qingyang

Abstract excerpt

OBJECTIVES: Genome-wide association studies (GWASs) have revealed many SNPs and genes associated with osteoporosis. However, influence of these SNPs and genes on the predisposition to osteoporosis is not fully understood. We aimed to identify osteoporosis GWASs-associated SNPs potentially influencing the binding affinity of transcription factors and miRNAs, and reveal enrichment signaling pathway and "hub" genes...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26930606
DOI: 10.1371/journal.pone.0150070
PMCID: PMC4773152

Genes

RUNX2
DKK1
ESR1
ESR2
FOXA1
LRP5
NFATC2
SOST
SOX9
STAT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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