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Gadolinium-based nanoparticles AGuIX and their combination with ionizing radiation trigger AMPK-dependent proinflammatory reprogramming of tumor-associated macrophages

2024-01-15

Abstract excerpt

<h4>Background</h4> Tumor-associated macrophages (TAMs) are essential components of the inflammatory microenvironment of tumors and are associated with poor clinical outcomes in the majority of cancers. TAMs mainly exhibit anti-inflammatory functions that promote and support the tissue remodeling, the immune suppression and the tumor growth. Regarding their plasticity, the functional reprogramming of anti-inflamm...

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Literature Corpus work
4ad48d3a-0aaf-558a-8c6e-7df4aaaa6000
DOI
10.1101/2024.01.12.575217
Open publication

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Gadolinium-based nanoparticles AGuIX and their combination with ionizing radiation trigger AMPK-dependent proinflammatory reprogramming of tumor-associated macrophagesDOI 10.1101/2024.01.12.575217
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