Article
The various functions and phenotypes of macrophages are also reflected in their responses to irradiation: A current overview.
International review of cell and molecular biology - 1 Jan 2023
Deloch Lisa, Rückert Michael, Weissmann Thomas, Lettmaier Sebastian, Titova Eva, Wolff Teresa, Weinrich Felix, Fietkau Rainer, Gaipl Udo S
Abstract excerpt
Macrophages are a vital part of the innate immune system that are involved in healthy biological processes but also in disease modulation and response to therapy. Ionizing radiation is commonly used in the treatment of cancer and, in a lower dose range, as additive therapy for inflammatory diseases. In general, lower doses of ionizing radiation are known to induce rather anti-inflammatory responses, while higher...
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