Article

Immunometabolic actions of trabectedin and lurbinectedin on human macrophages: Relevance for their antitumor activity

2023-03-07

Abstract excerpt

<title>Abstract</title> <p>In recent years, the central role of cell bioenergetics in regulating immune cell function and fate has been recognized, giving rise to the interest in immunometabolism, an area of research focused on the interaction between metabolic regulation and immune function. Thus, early metabolic changes associated with the polarization of macrophages into pro-inflammatory or pro-resolving cells...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 4a803549-aa2e-5abc-ad24-ab4dfe3881e6
DOI: 10.21203/rs.3.rs-2625385/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Immunometabolic actions of trabectedin and lurbinectedin on human macrophages: Relevance for their antitumor activityDOI 10.21203/rs.3.rs-2625385/v1Read

Immune cell metabolism in cancer drug resistance: Advances in target discovery and clinical translationSemantic proximity Read

Cancer immunometabolism: advent, challenges, and perspectiveSemantic proximity Read

The pivotal role of metabolism in shaping tumor-associated macrophages phenotype and function.Semantic proximity Read

The Metabolic Features of Tumor-Associated Macrophages: Opportunities for Immunotherapy?Semantic proximity Read

Metabolic changes in tumor cells and tumor-associated macrophages: A mutual relationship.Semantic proximity Read

Metabolic predictors of response to immune checkpoint blockade therapySemantic proximity Read

Biology of macrophage fate decision: Implication in inflammatory disordersSemantic proximity Read

ADAR1 Regulates Lipid Remodeling to Dictate Ferroptosis SensitivitySemantic proximity Read

Implication of metabolism in the polarization of tumor-associated-macrophages: the mass spectrometry-based point of view.Semantic proximity Read

Decoding molecular programs that define macrophage responses to tumor-derived cuesSemantic proximity Read

Inhibition of Glutamine Metabolism Suppresses Tumor Progression through Remodeling of the Macrophage Immune MicroenvironmentSemantic proximity Read