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Article

The Metabolic Features of Tumor-Associated Macrophages: Opportunities for Immunotherapy?

Analytical cellular pathology (Amsterdam) - 1 Jan 2021

Mojsilovic Sonja S, Mojsilovic Slavko, Villar Victor H, Santibanez Juan F

Abstract excerpt

Besides transformed cells, the tumors are composed of various cell types that contribute to undesirable tumor progression. Tumor-associated macrophages (TAMs) are the most abundant innate immune cells in the tumor microenvironment (TME). Within the TME, TAMs exhibit high plasticity and undergo specific functional metabolic alterations according to the availability of tumor tissue oxygen and nutrients, thus...

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Source

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Identifiers

PMID: 34476174
DOI: 10.1155/2021/5523055
PMCID: PMC8407977

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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