Article

CD155 regulates tumor growth and immune evasion in diffuse midline glioma

2025-09-12

Abstract excerpt

Diffuse midline glioma (DMG) is a devastating pediatric brain tumor with an unmet need for novel therapies. Immune checkpoint inhibitors have failed to prolong survival for DMG patients. In this study, we analyzed the expression of immune checkpoint molecules in human and murine DMG cells, as well as primary brain tumor samples, and identified CD155 as the most highly expressed. When murine DMG cells were co-cultu...

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Literature Corpus work: 4a6437ff-c8bd-56fb-9b83-318358c6ff5d
DOI: 10.1101/2025.09.09.674382

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