Article

FYN tyrosine kinase, a downstream target of receptor tyrosine kinases, modulates anti-glioma immune responses

2019-04-13

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> High grade gliomas are aggressive and immunosuppressive brain tumors. Molecular mechanisms that regulate the inhibitory immune tumor microenvironment (TME) and glioma progression remain poorly understood. FYN tyrosine kinase is a downstream target of the oncogenic receptor tyrosine kinases pathway and is overexpressed in human gliomas. FYN’s role in vivo in glioma growth re...

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Literature Corpus work: ea367205-8767-506d-ab08-3dba778ecd60
DOI: 10.1101/608505

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