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Article

Targeting Diffuse Midline Glioma with a novel anti-CD99 Antibody

2024-03-21

Abstract excerpt

Diffuse midline gliomas (DMGs) are devastating brain tumors that occur primarily in children. The salient feature of these tumors is the presence of a H3K27M mutation (K27M), associated with the worst prognosis. We identified the cell surface antigen CD99 as notably expressed in DMGs, particularly in K27M + DMGs. We found that the increased expression of CD99 in K27M + DMGs was a result of the onco-histone K27M...

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Identifiers and source

Literature Corpus work
3829ab0f-117e-555b-a393-599f8d3c89fb
DOI
10.1101/2024.03.19.585814
Open publication

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Targeting Diffuse Midline Glioma with a novel anti-CD99 AntibodyDOI 10.1101/2024.03.19.585814
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