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Article

Therapeutic Targets in Diffuse Midline Gliomas—An Emerging Landscape

13 Dec 2021

Abstract excerpt

Diffuse midline gliomas (DMGs) are invariably fatal pediatric brain tumours that are inherently resistant to conventional therapy. In recent years our understanding of the underlying molecular mechanisms of DMG tumorigenicity has resulted in the identification of novel targets and the development of a range of potential therapies, with multiple agents now being progressed to clinical translation to test their...

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PMID: 34944870
DOI: 10.3390/cancers13246251

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