Article

TMEM106B in Glioma: Diagnostic Potential and Mechanistic Implications

2025-10-29

Abstract excerpt

<title>Abstract</title> <p> <bold>Backgroup</bold> : Gliomas are the most common and aggressive primary brain tumors; their marked heterogeneity and profoundly immunosuppressive microenvironment drive treatment resistance and poor prognosis. TMEM106B, a lysosome-localized transmembrane protein studied in neurodegeneration, has an uncharacterized role in glioma. This study systematically defines TMEM106B express...

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Literature Corpus work: 201c66cb-edc0-5214-9ab1-5e7b4b5e40fd
DOI: 10.21203/rs.3.rs-7776786/v1

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