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Tolerance thresholds underlie responses to DNA damage during germline development

2024-01-07

Abstract excerpt

Selfish DNA modules like transposable elements (TEs) are particularly active in the germline, the lineage that passes genetic information across generations. New TE insertions can disrupt genes and impair the functionality and viability of germ cells. However, we find that in P - M hybrid dysgenesis in Drosophila , a sterility syndrome triggered by the P -element DNA transposon, germ cells harbour unexpectedly...

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Identifiers and source

Literature Corpus work
4a3b9613-6561-53e7-a027-366ead5a38ec
DOI
10.1101/2024.01.07.574510
Open publication

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Tolerance thresholds underlie responses to DNA damage during germline developmentDOI 10.1101/2024.01.07.574510
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