Article

p53 is required for female germline stem cell maintenance in <i>P</i> -element hybrid dysgenesis

2017-10-17

Abstract excerpt

<h4>ABSTRACT</h4> Hybrid dysgenesis is a sterility syndrome resulting from the mobilization of certain transposable elements in the Drosophila germline. Particularly extreme is the hybrid dysgenesis syndrome caused by P -element DNA transposons, in which dysgenic female ovaries often contain few or no germline cells. Those offspring that are produced from dysgenic germlines exhibit high rates of de novo mutati...

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Literature Corpus work: 40611fd3-1321-5f78-93f4-05d8fe77f246
DOI: 10.1101/204800

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