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QTL mapping of natural variation reveals that the developmental regulator <i>bruno</i> reduces tolerance to <i>P-</i> element transposition in the <i>Drosophila</i> female germline

2018-03-14

Abstract excerpt

<h4>ABSTRACT</h4> Transposable elements (TEs) are obligate genetic parasites that propagate in host genomes by replicating in germline nuclei, thereby ensuring transmission to offspring. This selfish replication not only produces deleterious mutations---in extreme cases, TE mobilization induces genotoxic stress that prohibits the production of viable gametes. Host genomes could reduce these fitness effects in two...

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Literature Corpus work
7999bedd-0df3-5307-843a-9882efdaa99b
DOI
10.1101/282541
Open publication

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QTL mapping of natural variation reveals that the developmental regulator <i>bruno</i> reduces tolerance to <i>P-</i> element transposition in the <i>Drosophila</i> female germlineDOI 10.1101/282541
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