Article

AMPK-p38 axis converts human pluripotent stem cells to naïve state

2022-03-31

Abstract excerpt

<h4>SUMMARY</h4> Pluripotent stem cells (PSCs) have been reported to exhibit two stages of pluripotency, ‘primed’ and ‘naïve’ states. Typical human PSCs (hPSCs) are in the primed state. Though several methods for conversion from primed to naïve state have been reported, the mechanism of the process is not fully understood. Here, we report that 5’ adenosine monophosphate-activated protein kinase (AMPK) and its dow...

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Literature Corpus work: 4a18387e-fd53-57b2-a5a2-6c52155f674f
DOI: 10.1101/2022.03.31.486536

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