Article

Resistance to Naïve and Formative Pluripotency Conversion in RSeT Human Embryonic Stem Cells

2024-02-17

Abstract excerpt

<h4>ABSTRACT</h4> One of the most important properties of human embryonic stem cells (hESCs) is related to their primed and naïve pluripotent states. Our previous meta-analysis indicates the existence of heterogeneous pluripotent states derived from diverse naïve protocols. In this study, we have characterized a commercial medium (RSeT)-based pluripotent state under various growth conditions. Notably, RSeT hESCs...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 991e6866-659e-502c-9753-e2ec203964a1
DOI: 10.1101/2024.02.16.580778

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Resistance to Naïve and Formative Pluripotency Conversion in RSeT Human Embryonic Stem CellsDOI 10.1101/2024.02.16.580778Read

Revealing cell populations catching the early stages of the human embryo development in naïve pluripotent stem cellsSemantic proximity Read

AMPK-p38 axis converts human pluripotent stem cells to naïve stateSemantic proximity Read

Pluripotent Stem Cells: Current Understanding and Future DirectionsSemantic proximity Read

The Divergent Pluripotent States in Mouse and Human CellsSemantic proximity Read

Transient let-7/miR-98 reprograms primed pluripotency to induce naive human PSCsSemantic proximity Read

Capture of mouse and human stem cells with features of formative pluripotencySemantic proximity Read

A new resource of clonal pluripotent human stem cell lines exhibiting inter- and intra-embryo consistency and variabilitySemantic proximity Read

The Naive State of Human Pluripotent Stem Cells: A Synthesis of Stem Cell and Preimplantation Embryo Transcriptome AnalysesSemantic proximity Read

Human archetypal pluripotent stem cells differentiate into trophoblast stem cells via endogenous BMP5/7 induction without transitioning through naive stateSemantic proximity Read

Efficient RNA-mediated reprogramming of human somatic cells to naïve pluripotency facilitated by tankyrase inhibitionSemantic proximity Read

Derivation of primed sheep embryonic stem cells and conversion to an intermediate naïve-like stateSemantic proximity Read

Decoding molecular markers and transcriptional circuitry of naive and primed states of human pluripotencySemantic proximity Read