Article

Derivation of human extended pluripotent stem cells in feeder-free condition

2020-10-18

Abstract excerpt

<h4>SUMMARY</h4> Human extended pluripotent stem cells (EPSCs), with bidirectional chimeric ability to contribute to both embryonic and extra-embryonic lineages, can be obtained and maintained by converting embryonic stem cells (ESCs) using chemicals. However, the transition system is based on inactivated mouse fibroblast, which greatly hinders the mechanistic studies of extended pluripotency and further applicat...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: cd017996-5677-52ff-a9fc-a21d6dfd56f5
DOI: 10.1101/2020.10.18.344259

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Derivation of human extended pluripotent stem cells in feeder-free conditionDOI 10.1101/2020.10.18.344259Read

An Efficient Chemical-Defined Condition for Generation of Human Induced Pluripotent Stem CellsSemantic proximity Read

Induced pluripotent stem cells: opportunities and challengesSemantic proximity Read

Generation of clinical-grade human induced pluripotent stem cells in Xeno-free conditionsSemantic proximity Read

High resolution multi-scale profiling of embryonic germ cell-like cells derivation reveals pluripotent state transitions in humansSemantic proximity Read

Expansion of pluripotent human embryonic stem cells on human feedersSemantic proximity Read

Novel autogenic feeders derived from human embryonic stem cells (hESCs) support an undifferentiated status of hESCs in xeno-free culture conditionsSemantic proximity Read

Urine-derived cells provide a readily accessible cell type for feeder-free mRNA reprogrammingSemantic proximity Read

Derivation of Human Induced Pluripotent Stem Cell (iPSC) Lines and Mechanism of Pluripotency: Historical Perspective and Recent AdvancesSemantic proximity Read

Efficient RNA-mediated reprogramming of human somatic cells to naïve pluripotency facilitated by tankyrase inhibitionSemantic proximity Read

Development and evaluation of a novel xeno-free culture medium for human-induced pluripotent stem cellsSemantic proximity Read

Metabolic remodeling during somatic cell reprogramming to induced pluripotent stem cells: involvement of hypoxia-inducible factor 1Semantic proximity Read

Derivation of Xeno-Free and GMP-Grade Human Embryonic Stem Cells – Platforms for Future Clinical ApplicationsSemantic proximity Read