Article

An Efficient Chemical-Defined Condition for Generation of Human Induced Pluripotent Stem Cells

2021-08-27

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Human induced pluripotent stem cells (hiPSCs) hold great potential in disease modeling, drug screening and cell therapy. However, efficiency and costs of hiPSCs preparation still need to be improved.<bold>Methods: </bold>We screened the compounds that target signaling pathways, epigenetic modifications or metabolic-process regulation to replace the growth factor...

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Literature Corpus work: 93598a6b-6e8f-565f-8fa7-f256f7d01cce
DOI: 10.21203/rs.3.rs-820071/v1

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