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The Divergent Pluripotent States in Mouse and Human Cells

16 Aug 2022

Abstract excerpt

Pluripotent stem cells (PSCs), which can self-renew and give rise to all cell types in all three germ layers, have great potential in regenerative medicine. Recent studies have shown that PSCs can have three distinct but interrelated pluripotent states: naive, formative, and primed. The PSCs of each state are derived from different stages of the early developing embryo and can be maintained in culture by...

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PMID: 36011370
DOI: 10.3390/genes13081459

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