Article

Decoding molecular markers and transcriptional circuitry of naive and primed states of human pluripotency

2020-04-20

Abstract excerpt

<h4>ABSTRACT</h4> Pluripotent stem cells (PSCs) have been observed to occur in two distinct states — naive and primed. Both naive and primed state PSCs can give rise to tissues of all the three germ layers in vitro but differ in their potential to generate germline chimera in vivo. Understanding the molecular mechanisms that govern these two states of pluripotency in human can open up a plethora of opportunitie...

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Literature Corpus work: f527a335-5b9e-56b3-a0f6-8efb03c7d041
DOI: 10.1101/2020.04.17.046037

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