Article

The genomic landscape of metastasis in treatment-naïve breast cancer models

2019-09-23

Abstract excerpt

Metastasis remains the principle cause of mortality for breast cancer and presents a critical challenge because secondary lesions are often refractory to conventional treatments. While specific genetic alterations are tightly linked to primary tumour development and progression, the role of genetic alteration in the metastatic process is not well-understood. To investigate how somatic evolution might contribute to...

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Literature Corpus work: 49c6a7c5-2d4c-549d-b428-9cceb2f6c9f5
DOI: 10.1101/777904

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