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Investigating the genomic landscape of mouse models of breast cancer metastasis

2025-01-19

Abstract excerpt

Metastasis remains a major cause of cancer mortality. AbstractThis study, expanding upon previous findings in the MMTV-PyMT model, investigated four independent mouse models, representing luminal (MMTV-PyMT, MMTV-Myc), HER2-amplified (MMTV-Her2) and triple negative (C3(1)TAg) breast cancer subtypes. Consistent with previous results, limited evidence for metastasis-associated somatic point mutations was found for a...

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Identifiers and source

Literature Corpus work
b89fffe6-d305-5e8a-be4b-83cdf34b9681
DOI
10.1101/2025.01.15.633216
Open publication

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Investigating the genomic landscape of mouse models of breast cancer metastasisDOI 10.1101/2025.01.15.633216
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