Article
The Influence of Cancer Molecular Subtypes and Treatment on the Mutation Spectrum in Metastatic Breast Cancers.
Cancer research - 1 Aug 2020
Verret Benjamin, Sourisseau Tony, Stefanovska Bojana, Mosele Fernanda, Tran-Dien Alicia, André Fabrice
Abstract excerpt
Next-generation sequencing has sparked the exploration of cancer genomes, with the aim of discovering the genetic etiology of the disease and proposing rationally designed therapeutic interventions. Driver gene alterations have been comprehensively charted, but the improvement of cancer patient management somewhat lags behind these basic breakthroughs. Recently, large-scale sequencing that focused on metastasis,...
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