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Article

Conserved phenotype and function of human brain border-associated macrophages in iPSC-derived models

2025-12-14

Abstract excerpt

<h4>SUMMARY</h4> Border-associated macrophages (BAMs) are increasingly implicated in protective brain functions including the removal of pathogenic material such as amyloid-beta (Aβ). However, there is a lack of available and deeply characterized human BAM models. Here, we report that postnatal transplantation of induced pluripotent stem (iPS) cell-derived hematopoietic progenitors to the murine brain sufficientl...

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Literature Corpus work
49b56eb3-6358-5efe-8d13-771614ad5a63
DOI
10.64898/2025.12.11.693582
Open publication

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Conserved phenotype and function of human brain border-associated macrophages in iPSC-derived modelsDOI 10.64898/2025.12.11.693582
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