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Modular safe-harbor transgene insertion (MosTI) for targeted single-copy and extrachromosomal array integration in <i>C. elegans</i>

2022-04-19

Abstract excerpt

Efficient and reproducible transgenesis facilitates and accelerates research using genetic model organisms. Here we describe a mo dular s afe harbor transgene insertion (MosTI) for use in C. elegans which improves targeted insertion of single-copy transgenes by homology directed repair and targeted integration of extrachromosomal arrays by non-homologous end-joining. MosTI allows easy conversion between selecti...

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Identifiers and source

Literature Corpus work
49a848db-9999-5970-b373-0e0c7db95f22
DOI
10.1101/2022.04.19.488726
Open publication

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Modular safe-harbor transgene insertion (MosTI) for targeted single-copy and extrachromosomal array integration in <i>C. elegans</i>DOI 10.1101/2022.04.19.488726
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