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Article

High-throughput library transgenesis in Caenorhabditis elegans via Transgenic Arrays Resulting in Diversity of Integrated Sequences (TARDIS).

eLife - 4 Jul 2023

Stevenson Zachary C, Moerdyk-Schauwecker Megan J, Banse Stephen A, Patel Dhaval S, Lu Hang, Phillips Patrick C

Abstract excerpt

High-throughput transgenesis using synthetic DNA libraries is a powerful method for systematically exploring genetic function. Diverse synthesized libraries have been used for protein engineering, identification of protein-protein interactions, characterization of promoter libraries, developmental and evolutionary lineage tracking, and various other exploratory assays. However, the need for library transgenesis...

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Share to Animals, Genetically Modified
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Barcoding, Taxonomic

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Share to Promoter Regions, Genetic

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Source

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Identifiers

PMID: 37401921
DOI: 10.7554/eLife.84831
PMCID: PMC10328503

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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