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Article

Genome-wide RNAi screen for regulators of UPR <sup>mt</sup> in <i>Caenorhabditis elegans</i> mutants with defects in mitochondrial fusion

2020-08-01

Abstract excerpt

<h4>ABSTRACT</h4> The disruption of mitochondrial dynamics has detrimental consequences for mitochondrial and cellular homeostasis and leads to the activation of the mitochondrial unfolded protein response (UPR mt ), a quality control mechanism that adjusts cellular metabolism and restores homeostasis. To identify genes involved in the induction of UPR mt in response to a block in mitochondrial fusion, we perfo...

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Literature Corpus work
49a1f77c-d788-5787-b0ef-556cc6616c5c
DOI
10.1101/2020.07.31.230441
Open publication

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Genome-wide RNAi screen for regulators of UPR <sup>mt</sup> in <i>Caenorhabditis elegans</i> mutants with defects in mitochondrial fusionDOI 10.1101/2020.07.31.230441
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