Article

<i>VPS13D</i> mutations affect mitochondrial homeostasis and locomotion in <i>Caenorhabditis elegans</i>

2025-01-25

Abstract excerpt

Mitochondria control cellular metabolism, serve as hubs for signaling and organelle communication, and are important for the health and survival of cells. VPS13D encodes a cytoplasmic lipid transfer protein that regulates mitochondrial morphology, mitochondria and endoplasmic reticulum (ER) contact, quality control of mitochondria. VPS13D mutations have been reported in patients displaying ataxic and spastic gai...

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Literature Corpus work: 5f9186b6-9c27-5bd4-8e7b-a3ff8133b9fe
DOI: 10.1101/2025.01.22.634397

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